Zif Forte Capsule N/A

Indications

This capsule is indicated for the treatment and prophylaxis of iron, folic acid, zinc, vitamin-B complex and vitamin-C deficiency, especially during pregnancy and lactation.

Composition

Each capsule contains

Elemental Iron [as Carbonyl iron] INN 50 mg

Zinc Sulphate Monohydrate BP 61.80 mg equivalent to Zinc 22.50 mg

Folic Acid BP 0.5mg

Nicotinamide BP 10 mg

Riboflavin BP 2 mg

Pyridoxine Hydrochloride BP 1 mg

Ascorbic Acid USP 50 mg

Thiamine Mononitrate BP 2 mg.

Pharmacology

Carbonyl Iron is more effective and safer choice of Iron supplementation as it has higher bioavailability, low toxicity and better Gl tolerance.

Folic acid is required to maintain normal healthy development of the neural tube and is vital for cell division from a single cell to a fully developed baby.

Vitamin B Complex is required for the growth and development of unborn babies.

Vitamin C plays a role In the structure of collagen in the fetal membrane.

Zinc is a critical nutrient for fetal growth & development, central nervous system development & function and ensures better maternal & infant health

Dosage & Administration

Adult: One capsule daily before food or as directed by the physician.

Use in Children & Adolescents: Upon consultation with a doctor, recommended to use in children & adolescents.

* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'

Interaction

Carbonyl Iron decreases the absorption of tetracycline antibiotics, quinolone antibiotics, levodopa, levothyroxine, methyldopa and penicillamine. Folic Acid interacts with antiepileptics, so plasma concentrations of phenobarbital, phenytoin and primidone are possibly reduced.

Contraindications

It is contraindicated in patients with a known hypersensitivity to any of the ingredients. Iron therapy is contraindicated in the presence of haemolytic anaemia.

Side Effects

Allergic sensitization has been reported following oral administration of Folic acid. Oral iron preparation may cause constipation, particularly in older patients.

Pregnancy & Lactation

Use of any drug during first trimester of pregnancy should be avoided if possible. Thus administration of Iron during the first trimester requires definite evidence of Iron deficiency. Prophylaxis of Iron deficiency where inadequate diet calls for supplementary Zinc and Folic acid is justified during the remainder of the pregnancy.

Precautions & Warnings

Care should be taken in patients who may develop iron overload, such as those with hemochromatosis, hemolytic anemia or red cell aplasia. Iron chelates with tetracycline and absorption may be impaired.

Overdose Effects

Symptoms of Carbonyl Iron include decreased energy, nausea, abdominal pain, tarry stool, weak, rapid pulse, fever, coma, seizures.

Therapeutic Class

Iron, Vitamin & Mineral Combined preparation

Storage Conditions

Store at temperature not exceeding 30°C in a dry place. Protect from moisture.