Live Chat
0 ITEMS0

0 ITEMS

৳
0
Dhaka

Selected City: Dhaka

Use my current Location


Change City

EN 

|

 বাং

Dhaka

Use my current Location


Change City

Selected City: Dhaka

Grocery
Pharmacy
Cookups
  • Offers
  • Egg Club
  • Daily Deals
  • Favourites
  • Common Conditions 
  • Sexual Wellness
  • Birth Control Contraceptives
  • Vitamins & Supplements 
  • Medical Devices
  • Medical Accessories
  • Personal Care 
  • Health & Wellness 
  • Baby Care 
  • Premium Care
  • Food Aid
  • Recipes
Help
File a complaint

    Selomet Tablet 50mg

    10 tablets
    ৳20
    0
    in bag

    Product Information

    SELOMET

    Selomet®(Metoprolol)

    Presentation

    Selomet-25 tablet: Blue, shield shaped, scored tablet, having engraved on other side; each tablet contains Metoprolol Tartrate USP

    25 mg.

    Selomet-50 tablet: Blue, parallel capsule shaped, scored tablet, having engraved on other side; each tablet contains Metoprolol

    Tartrate USP 50 mg.

    Indications

    ln the management of hypertension and angina pectoris. Cardiac arrhythmias, especially supraventricular tachyarrhythmias. Adjunct

    to the treatment of hyperthyroidism. Early intervention with Metoprolol in acute myocardial infarction reduces infarct size and

    the incidence of ventricular fibrillation. Pain relief may also decrease the need for opiate analgesics. Metoprolol has been shown

    to reduce mortality when administered to patients with acute myocardial infarction.

    Dosage and administration

    Hypertension: Total daily dosage Metoprolol 100 – 400 mg to be given as a single or twice daily dose. The starting dose is 100 mg

    (two Selomet-50 tablets) per day. This may be increased by 100 mg per day at weekly intervals. lf full control is not achieved

    using a single daily dose, a b.i.d. regimen should be initiated. Combination therapy with a diuretic or other anti-hypertensive

    agent may also be considered.

    Angina: Usually Metoprolol 50 mg (one Selomet-50 tablet) to 100 mg (two Selomet-50 tablets) twice or three times daily.

    Cardiac arrhythmias: Metoprolol 50 mg (one Selomet-50 tablet) b.i.d or t.i.d should usually control the condition. It necessary

    the dose can be increased up to 300 mg per day in divided doses. Following the treatment of an acute arrhythmia with Metoprolol

    injection, continuation therapy with Metoprolol tablets should be initiated 4-6 hours later. The initial oral dose should not

    exceed 50 mg t.i.d.

    Hyperthyroidism: Metoprolol 50 mg (one Selomet-50 tablet) four times a day.The dose should be reduced as the euthyroid state is

    achieved.

    Myocardial infarction: Orally, therapy should commence 15 minutes after the last injection with 50 mg every 6 hours for 48 hours.

    Patients who fail to tolerate the full intravenous dose should be given half the suggested oral dose. Maintenance – The usual

    maintenance dose is 200 mg daily given in divided doses. Elderly’ There are no special dosage requirements in otherwise

    healthy elderly patients. Signidcant hepatic dysfunction: A reduction in dosage may be necessary.

    Contra-indications, warnings, etc.

    Contra-indications: AV block, Uncontrolled heart failure, severe bradycardia, sick-sinus syndrome, cardiogenic shock and severe

    peripheral arterial disease. Known hypersensitivity to Metoprolol or other B-blockers. Metoprolol is also contra-indicated when

    myocardial infarction is complicated by significant bradycardia, first degree heart block, systolic hypotension (<100mmHg)

    and/or severe heart failure. Warnings: Metoprolol may aggravate bradycardia, symptoms of peripheral arterial circulatory disorders

    and anaphylactic shock. Abrupt interruption of B-blockers is to be avoided. When possible, Metoprolol should be withdrawn

    gradually over a period of 10 days, in diminishing doses to 25 mg daily for the last 6 days. During its withdrawal patients should

    be kept under close surveillance, especially those with known ischaemic heart disease. Metoprolol may be administered when heart

    failure has been controlled. Digitalisation and/or diuretic therapy should also be considered for patients with a history of heart

    failure, or patients known to have a poor cardiac reserve. Although cardioselective B-blockers may have less effect on lung

    function than non-selective [3-blockers, as with all B-blockers these should be avoided in patients with reversible obstructive

    ainlvays disease unless there are compelling clinical reasons for their use. When administration is necessary, use of a

    B2-bronchodilator (e.g. terbutaline) may be advisable in some patients. In labile and insulin-dependent diabetes it may be

    necessary to adjust the hypoglycaemic therapy. In patients with a phaeochromocytoma, an on-blocker should be given concomitantly.

    In the presence of liver cirrhosis the bioavailability of Metoprolol may be increased. The administration of adrenaline to

    patients undergoing [5-blockade can result in an increase in blood pressure and bradycardia, although this is less likely to occur

    with B1-selective drugs. Metoprolol therapy must be reported to the anaesthetist prior to general anaesthesia. If withdrawal of

    Metoprolol is considered desirable, this should if possible be completed at least 48 hours before general anaesthesia. However, in

    some patients it may be desirable to employ a Bblocker as premedication. By shielding the heart against the effects of stress the

    B-blocker may prevent excessive sympathetic stimulation provoking cardiac arrhythmias or acute coronary insufficiency. If a

    B-blocker is given for this purpose, an anaesthetic with little negative inotropic activity should be selected to minimise the

    risk olmyocardial depression.

    Use in pregnancy and lactation: Metoprolol should not be used in pregnancy or lactating mothers unless the physician considers

    that the benefit outweighs the possible hazard to the foetus/infant.

    Drug interactions: The effects of Metoprolol and other antihypertensive drugs on blood pressure are usually additive, and care

    should be taken to avoid hypotension. However, combinations of antihypertensive drugs may often be used with benefit to improve

    control of hypertension. Metoprolol can reduce myocardial contractility and impair intracardiac conduction. Care should be

    exercised when drugs with similar activity, e.g. antiarrhythmic agents, general anaesthetics, are given concurrently. Like all

    other B-blockers, Metoprolol should not be given in combination with verapamil since this may cause bradycardia, hypotension and

    asystole. Care should also be exercised when [5-blockers are given in combination with sympathetic ganglion blocking agents, other

    B-blockers (i.e. eye drops) or MAO inhibitors. lf combination treatment with clonidine is to be discontinued, Metoprolol should be

    withdrawn several days before clonidine. As [3-blockers may affect the peripheral circulation, care should be exercised when drugs

    with similar activity e.g. ergotamine are given concurrently Metoprolol will antagonise the [31 -effects of sympathomimetic agents

    but should have little influence on the bronchodilator effects of B2- agonists at normal therapeutic doses. Enzyme inducing agents

    (e.g. rifampicin) may reduce plasma concentrations of Metoprolol, whereas enzyme inhibitors (e.g.cimetidine) may increase plasma

    concentrations. Metoprolol may impair the elimination of lignocaine. lndomethacin may reduce the antihypertensive effect of

    [3-blockers.

    Side-effects: These are usually mild and infrequent. The most common appear to be lassitude, GI disturbances (nausea, vomiting or

    abdominal pain) and disturbances of sleep pattern. ln many cases these effects have been transient or have disappeared after a

    reduction in dosage. Effects related to the CNS which have been reported occasionally are dizziness and headache and

    rarely paraesthesia, muscle cramps, depression and decreased mental alertness. There have also been isolated reports of

    personality disorders. Cardiovascular effects which have been reported occasionally are bradycardia, postural hypotension and

    rarely, heart failure, palpitation, cardiac arrhythmias, Ftaynauds phenomenon, peripheral oedema and precordial pain. There have

    also been isolated reports of cardiac conduction abnormalities and gangrene in patients with preexisting severe peripheral

    circulatory disorders. Common gastro-intestinal disturbances have been described above but rarely diarrhoea or constipation also

    occur and there have been isolated cases of dry mouth and abnormal liver function. Skin rashes (urticaria,

    psoriasiform, dystrophic skin lesions) and positive anti-nuclear antibodies (not associated with SLE) occur rarely. Isolated cases

    of photosensitivity, increased sweating and alopecia have been reported. Flespiratory effects include occasional reports of

    dyspnoea on exertion and rare reports of bronchospasm and isolated cases of rhinitis. Isolated cases of weight gain,

    thrombocytopenia, disturbances of vision, conjunctivitis, tinnitus and dry or irritated eyes have also been reported. The reported

    incidence of skin rashes and/or dry eyes is small and in most cases the symptoms have cleared when treatment was withdrawn.

    Discontinuation of the drug should be considered if any such reaction is not otherwise explicable.

    Overdosage: Poisoning due to an overdose of metoprolol may lead to severe hypotension, sinus bradycardia, atrioventricular block,

    heart failure, cardiogenic shock, cardiac arrest, bronchospasm, impairment of consciousness, coma, nausea, vomiting, cyanosis,

    hypoglycaemia and, occasionally, hyperkalaemia. The first manifestations usually appear 20 minutes to 2 hours after drug

    ingestion. Treatment: Treatment should include close monitoring of cardiovascular, respiratory and renal function, and blood

    glucose and electrolytes. Further absorption may be prevented by induction of vomiting, gastric lavage or administration of

    activated-charcoal if ingestion is recent. Cardiovascular complications should be treated symptomatically, which may require the

    use of sympathomimetic agents (e.g. noradrenaline, metaramionl), atropine or inotropic agents (e.g. dopamine, dobutamine).

    Temporary pacing may be required for AV block. Glucagon can reverse the effects of excessive B-blockade, given in a dose of 1-10

    mg intravenously. Intravenous B2-stimulants e.g. terbutaline may be required to relieve bronchospasm. Metoprolol cannot be

    effectively removed by haemodialysis.

    Pharmaceutical precautions

    Store in a cool and dry place, protected from light.

    Packaging quantities

    Selomet-25 tablet: Cartons containing 30 tablets in blister.

    Selomet-50 tablet: Cartons containing 30 tablets in blister.

    • 30 minute delivery
    • Cash on delivery
    • Pay with

    Chaldal logo

    Chaldal.com is an online shop available in Dhaka, Chattogram, Jashore, Khulna and Narayanganj. We believe time is valuable to our fellow residents, and that they should not have to waste hours in traffic, brave bad weather and wait in line just to buy basic necessities like eggs! This is why Chaldal delivers everything you need right at your door-step and at no additional cost.

    Customer Service

    • Contact Us
    • FAQ

    About Chaldal

    • Privacy Policy
    • Terms of Use

    For Business

    • Corporate
    16710
    or email[email protected]