Nitro SR Tablet 2.6mg
10 tabletsProduct Information
NITRO-SR
Nitro-SR®Nitroglycerin USP 2.6 mg tablet
Indications
Prevention and treatment of effort and vasospastic angina: Supplementary treatment if heart failure refractory to digitalis and
diuretic treatment.
Dosage and administration
Adults and elderly patients: Dosage should be tailored to the requirements of the individual patient depending on the severity of
illness and the occurrence of side effects but will usually be 1 or 2 tablet taken 2-3 times daily before meals. Children: Not
recommended.
Contra-indications, warnings, etc
Contraindications: Nitroglycerin USP tablet should not be used in patients with marked anaemia, head trauma, cerebral haemorrhage
or incipient glaucoma. Sildenafil has been shown to potentiate the hypotnsive effects of nitrates, and its co-administration with
nitrates or nitric oxide donors is therefore contraindicated. Warnings and Precautions: As will other drugs for the treatment of
angina pectoris, abrupt discontinuation of therapy may lead to exacerbation of symptoms. When discontinuing long term treatment,
the dosage should be reduced gradually over several days. Drug-interactions: Nitroglycerin may potentiate the effects of
peripheral vasodilators. The hypotensive effects of nitrates are potentiated by concurrent administration of sildenafil.
Pregnancy and lactation: There is no evidence relating to the safety of nitrates in pregnancy and lactation. Nitroglycerin should
be administered to pregnant women and nursing mothers unless considered essential by the physician.
Side effects: Headache, dizziness, mild gastrointestinal symptoms may occur. They disappear on dosage reduction and usually do
not necessitate the discontinuation of the treatment.
Overdosage: ln the case of overdosage, the likely symptomatology may be peripheral vasodilation with a fall in blood pressure and
reflex tachycardia. In such an event, monitoring of cardiac function and general supportive measures should be used. If not
successful, circulating plasma volume should be increased by substitution of fluid. ln life-threatening situations, administration
of vasopressors should be considered.
Pharmaceutical precautions
Store in a cool and dry place, protected from light.
Package quantities:
Nitro-SR Tablet: Cartons containing 30 tablets in Alu-PVDC pack.