Econate Cream 1%/10gm

PRESENTATION

Econate cream: Each gram cream contains Econazole Nitrate BP 10 mg.

Econate-G cream: Each gram cream contains Econazole Nitrate BP 10 mg.

Econate VT: Each vaginal tablet contains Econazole Nitrate BP 150 mg.

DESCRIPTION

Econazole Nitrate is a broad-spectrum antifungal agent. The range of action of Econazole covers all dermatomycoses caused by the

following pathogens :

Dermatophytes, such as Trichophyton, Epidermophyton, Microsporum, Cladosporium and others.

Yeasts, such as Candida, Cryptococcus neoformans, Torulopsis, Rhodotorula and others.

Moulds and other Fungi, such as Scopulariopsis brevicaulis, Aspergillus flavus, Histoplasma capsulatam, Blastomyces dermatitidis

and others. As well as Malassezia furfur and Nocardia minutissima.

Moreover, it has antibacterial effect on Gram-positive cocci and bacilli, including Streptococcus pyogens and Staphylococcus

aureus.

It is also effective against Trichomonus vaginalis

INDICATIONS

Econate Cream: All fungal skin infections due to dermatophytes, yeasts, moulds and other fungi. These include Vulvo-vaginal

candidiasis, Candidial napkin rash, and other candidial infection, Ringworm (tinea) infections, Athlete's foot, Paronychia,

Pityriasis versicolor and Balanitis.

Econate-G Cream: Vulvo-vaginal candidiasis or any other fungal infection of vagina.

Econate VT: Vulvo-vaginal candidiasis or any other fungal infection of vagina.

For the treatment of onychomycosis, local therapy with Econazole cream, combined with an oral antimycotic, is recommended.

DOSAGE & ADMINISTRATION

Econazole Cream is applied to the affected skin areas once or twice daily, in the morning and/or in the evening and gently rubbed

in with the clean finger. For mycoses of the hands, application is recommended following each washing of the hands. For the

treatment of onychomycosis, occlusive dressings are recommended.

Econate-G Cream is applied with the applicator par vaginally once or twice daily.

Econate VT is applied with the applicator par vaginally one tablet once or twice daily.

In order to prevent relapse, treatment should be continued for 2 weeks after clinical cure.

SIDE EFFECTS

Rarely, transient local mild irritation, itching & redness may occur immediately after application. Econazole has minimal allergic

effect. It is well tolerated, even by delicate skin. Local irritations are not likely to occur, except in rare cases, e.g., in

eczematous skin areas. In such cases, anti-eczematous treatment is recommended for several days before therapy with Econazole is

initiated.

PRECAUTIONS

Hypersensitivity has rarely been recorded. If something like this occur, administration of the product should be discontinued. The

infected area should be kept clean and dry during treatment.

USE IN PREGNANCY & LACTATION

During pregnancy: There is no information of any abnormality or adverse event in neonates while Econazole Cream / VT had been used

during pregnancy.

During lactation: As the systemic absorption of Econazole Nitrate cream is extremely low after topical/vaginal use, excretion in

breastmilk is likely to be negligible. So, it can be used topically/vaginally during lactation if needed.

OVER DOSE

Econazole Cream / VT is intended for topical and vaginal use. If accidental ingestion of large quantities of the product occurs,

an appropriate method of gastric emptying may be used if considered desirable.

COMMERCIAL PACK

Econate cream: Tube containing 10 gm of Econazole Nitrate cream.

Econate-G cream : Tube containing 30 gm of Econazole Nitrate cream.

Econate VT Tablet: Each box contains 1 strip of 3 tablets.