Cogniz Tablet 500mg

Product Information

COGNIZ

Cogniz®

Citicoline

Presentation

Cogniz 500 tablet: White, oval-shaped tablet,    engraved on one side; each tablet contains Citicoline INN 500 mg.

Indications

Cerebrovascular diseases – e.g. from ischaemia due to stroke, where Citicoline accelerates the recovery of consciousness and

overcoming motor deficit.

Head Trauma of varying severity: Citicoline accelerates the recovery from post-traumatic coma and the recuperation of walking

ability, achieved a better final functional result and reduced hospital stay.

Cognitive disorders of diverse aetiology – e.g. senile cognitive impairment which is secondary to degenerative diseases (e.g.

Alzheimer’s disease) and to chronic cerebral vascular disease. Citicoline improves scores on cognitive evaluation scales and

slowed the progression of Alzheimer’s disease.

Parkinson’s disease: Citicoline has also been shown to be effective as co-therapy for Parkinson’s disease. Citicoline increases

striatal dopamine and tyrosine hydroxylase synthesis.

Dosage and administration

For immediate treatment of stroke due to a clot (ischemic stroke): 500-2000 mg of Citicoline per day starting within 24 hours of

stroke.

For ongoing disease of the blood vessels that serve the brain (chronic cerebro-vascular disease): 600 mg of Citicoline per day.

For decline in thinking skills due to age: 1000-2000 mg of Citicoline per day.

Contra-indications, warning, etc.

Contra-indications:

-Gotonia (predominance of tone of parasympathetic part of vegetative nervous system);

-Children and teenage age before 18 years (in connection with absence of data);

– Hypersensitivity to components of drug.

Warnings: Citicoline may cause hypotension and incase of necessary the hypotensive effect can be treated with corticosteroids or

sympathomymetics.

Precautions: Citicoline is known to cause increased dizziness and drowsiness in users. As a result, it is strongly recommended

that users do not operate any type of machinery throughout the course of treatment.

Use in pregnancy and lactations: There is inadequate evidence of safe use of Citicoline in human pregnancy. Citicoline should be

used in pregnancy and lactation only if the potential benefits justify the potential risks.

Drug interactions: Citicoline potentiates the effects of Levodopa. Citicoline must not be used with medicines containing

Meclophenoxate or (Centrophenoxine).

Side effects: The most common side effects associated with using Citicoline are: headache, irregular heartbeat, diarrhea, low

blood pressure, dizziness, lightheadedness, vomiting, nausea.

The severe side effects which are very rare include: tightening of the chest, closing of the throat, severe skin rash, hives,

difficulty in breathing, swelling of the lips, tongue, throat and mouth.

Pharmaceutical precautions

Store in a cool and dry place, protected from light.

Packaging quantity

Cogniz 500 tablet: Carton containing 12 tablets in Alu-Alu blister.

Manufactured by

UniMed & UniHealth Manufacturers Ltd.

Gazipur, Bangladesh

® Registered Trademark