Caloprid Tablet 2mg

Indication:

CalopridTM is indicated for symptomatic treatment of chronic constipation in adults in whom laxatives fail to provide adequate

relief.

Dosage & Administration:

Chronic Constipation

Adults

2 mg once daily with or without food, at any time of the day. Due to the specific mode of action of Prucalopride (stimulation of

propulsive motility), exceeding the daily dose of 2 mg is not expected to increase efficacy. Older people Start with 1 mg once

daily; if needed the dose can be increased to 2 mg once daily.

Children

Prucalopride should not be used in children and adolescents younger than 18 years

Renal Impairment

The dose for patients with severe renal impairment (GFR < 30 ml/min/1.73 m2) is 1 mg once daily. No dose adjustment is required

for patients with mild to moderate renal impairment.

Hepatic Impairment

Patients with severe hepatic impairment (Child-Pugh class C) start with 1 mg once daily which may be increased to 2 mg if required

to improve efficacy and if the 1 mg dose is well tolerated. No dose adjustment is required for patients with mild to moderate

hepatic impairment.

Preparation:

CalopridTM 1 tablet: Each box contains in 2x10’s tablets in alu-alu blister pack.

CalopridTM 2 tablet: Each box contains in 2x10’s tablets in alu-alu blister pack.