Tenoren Tablet 50mg
20 tabletsTenoren
Description
Tenoren is the preparation of Atenolol, It is a synthetic, P-selective (cardioselective) Atenolol
adrenoreceptor blocking agent without membrane stabilizing or intrinsic sympathomimetic activity
Indications
Tenoren is indicated for the following conditions
Hypertension
Angina Pectoris
-Cardiac Anhythmia) -Acuto Myocardial Infarction
Dosage & administration
Hypertension: The initial dose is 50 mg once daily. If an optimal response is not achieved, the dose should be increased to 100 mg once a day. Angina pectoris: The initial dose is 50 mg once daily. If an optimal response is not achieved within one week, the dose should be increased to 100 mg once a day. Some patients may require a dose of 200 mg once a day for optimal effect Cardiac arrhythmia The initial dose is 25-50 mg once daily. If an optimal response is
not achieved, the dose should be increased to 100 mg once a day.
Acute myocardial infarction: Atenolol can be given orally 50 mg twice a day or 100 mg
once a day after initial therapy with intravenous Atenolol (Patients who present within 12
hours of onset of chest pain, intravenous Atenolol 5 mg should be injected over 5
minutes followed by another 5 mg intravenous injection 10 minutes later. In patients who
tolerate the full intravenous dose, e.g. 10 mg. Tenoren 50 mg tablet should be initiated
10 minutes after the last intravenous dose followed by another 50 mg oral dose 12
hours later)
Elderly & renal impairment: 25 mg once a day.
Tenoren
Patients on hemodialysis: 25 mg or 50 mg after each dialysis; this should be done under hospital supervision as marked falls in blood pressure may occur.
Children: Safety and effectiveness in pediatric patients have not been established.
Use in pregnancy & lactation
Atenolol can cause fetal harm when administered to a pregnant woman. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus. Caution should be exercised when Atenolol is administered to a woman, who is breastfeeding
Precautions Patients already on a p-blocker must be evaluated carefully before Atenolol is
administered. Initial and subsequent Atenolol dosages can be adjusted downward
depending on clinical observations including pulse and blood pressure. Atenolol may
aggravate peripheral arterial circulatory disorders.
Side effects
In general, Atenolol is well tolerated although in a small undesired events have been reported, such as hallucinations, headache, impotence, purpura, thrombocytopenia, visual disturbance, sick sinus syndrome, dry mouth, reversible mental depression and dry eyes.
Contraindications
Atenolol is contraindicated in sinus bradycardia, heart block greater than first degree. cardiogenic shock and overt cardiac failure. It is also contraindicated in patients with a history of hypersensitivity to Atenolol or any of the drug product's components.
Warnings
In patients who have congestive heart failure controlled by digitalis and/or diuretics, Atenolol should be administered cautiously. Continued depression of the myocardium with p-blocking agents over a period of time can, in some cases, lead to cardiac failure.
Drug interactions
Combined use of B-blockers and calcium channel blockers with negative inotropic effects eg verapamil and diltiazem can cause severe hypotension, bradycardia and cardiac failure. Digitalis glycosides, in association with p-blockers, may increase atrio-ventricular conduction time. In addition ẞ-blockers have interaction with clonidine that may result in severe rebound hypertension, Concurrent administration of indomethacin reduces the antihypertensive action.
Pharmaceutical precautions
Tenoren
Keep away from the reach of
from light.
children. Store in a cool (below 30°C) & dry place. Protect
Presentation Tenoren 25 mg Tablet. Each tablet contains Atenolol BP 25 mg
Tenoren 50 mg Tablet: Each tablet contains Atenolol BP 50 mg.
Tenoren 100 mg Tablet Each tablet contains Atenolol BP 100 mg.
Package quantities Tenoren 25 mg Tablet: Carton of 50 tablets in blister.
Tenoren 50 mg Tablet: Carton of 150 tablets in blister.
Tenoren 100 mg Tablet: Carton of 100 tablets in blister.
For export
Tenoren® 50 mg Tablet: Carton of 30 tablets, 100 tablets and 150 tablets in blister. Tenoren® 100 mg Tablet: Carton of 30 tablets and 100 tablets in blister.
Registered Trade Mark
Advanced Chemical ACI Industries Limited
7. Hajeegon Road, Godny Narayangon Bangladesh